A Reconfigurable Hardware Realization for Real-Time Simulation of Cardiac Excitation and Conduction

Mahmud, Farhanahani and Adon, Nur Atiqah and Othman, Norliza and Hakim, Ade Anggian and Morsin, Marlia and Jabbar, Mohamad Hairol (2024) A Reconfigurable Hardware Realization for Real-Time Simulation of Cardiac Excitation and Conduction. International Journal Of Integrated Engineering, 16 (1). pp. 272-281. ISSN 2600-7916

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Abstract

Dynamic simulation of complex cardiac excitation and conduction requires high computational time. Thus, the hardware techniques that can run in real-time simulation were introduced. However, according to existing studies, the hardware simulation requires high power consumption and involves a large size of the physical parts. Due to the drawbacks, this research presents the adaptation of nonlinear Ordinary Differential Equation (ODE)-based cardiac excitable models of Luo-Rudy Phase I (LR-I) and FitzHugh-Nagumo (FHN) in a reconfigurable hardware of field-programmable gate array (FPGA). FPGA rapid prototyping using MATLAB Hardware Description Language (HDL) Coder was used to convert a fixed-point MATLAB Simulink blocks design of the cardiac models into a synthesizable VHSIC Hardware Description Language (VHDL) code and verified using the FPGA-In-the Loop (FIL) Co-simulator. The Xilinx FPGA Virtex-6 XC6VLX240T ML605 evaluation board was chosen as the FPGA platform. The cardiac excitation response characteristics using the LR-I model and the simulations of reentrant initiation and annihilation using the FHN model were verified in Virtex-6 FPGA. This means a new real-time simulation-based analysis technique of cardiac electrical excitation and conduction was successfully developed using the reconfigurable hardware.

Item Type:	Article
Uncontrolled Keywords:	FPGA, Virtex-6, cardiac excitation, reentrant, Luo-Rudy model, FitzHugh-Nagumo, HDL Coder
Subjects:	Q Science > QP Physiology
Divisions:	Faculty of Electrical and Electronic Engineering > FKEE
Depositing User:	Mr. Mohamad Zulkhibri Rahmad
Date Deposited:	31 Jan 2025 08:08
Last Modified:	31 Jan 2025 08:09
URI:	http://eprints.uthm.edu.my/id/eprint/12430

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