Uric Acid Concentration-Surface Tension Level Through Reflective Intensity of Optical Fibre Sensor

Mohd Taib, Nur Athirah and Mohamad Azlan Gan, Nur Najihah Gan and Adnan, Nurul Nadia and Ain, Quratul (2025) Uric Acid Concentration-Surface Tension Level Through Reflective Intensity of Optical Fibre Sensor. Journal of Advanced Research Design, 125 (1). pp. 42-52. ISSN 2289-7984

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Abstract

Human body fluids are regarded as desirable sources for biological markers due to the fact the altered protein expression profiles reflect the change of physiological states and cell networks of the diseased tissue/organ. Owning to several advantages including low invasiveness, low cost and rapid sample collection and processing makes the evaluation of human body fluid has become one of the most promising approaches in disease diagnosis and prognosis to discover biomarkers or reveal pathophysiological mechanisms for human disease. Surface tension is a surface characteristic that related to the forces of molecules residing at the interface. The presence of surface-active substance in biological or body fluids which adsorb at interface influences the norm surface tension value. Such the changes indicate valuable signs in medical field particularly in pathological states. Thus, in this study we demonstrate the effect of concentration towards the surface tension by employing the concept of light reflective intensity modulation as a function of displacement since the meniscus formation is one of surface tension characteristics. A key reference parameter for examining 0 mg/dl – 10 mg/dl of uric acid was evaluated. It is found that the fingerprint of each sample has two maximum output voltages located at approximately two stable positions. The surface tension value decreases from 71.849 mN/m to 70.238 mN/m in the change of 0 ppm to 500 ppm with deviation of 2.6 V to 3.5 V.

Item Type:	Article
Uncontrolled Keywords:	Uric acid; surface tension; concentration; optical fibre sensor
Subjects:	Q Science > QC Physics
Divisions:	Faculty of Applied Science and Technology > FAST
Depositing User:	Mr. Mohamad Zulkhibri Rahmad
Date Deposited:	12 Aug 2025 00:06
Last Modified:	12 Aug 2025 00:07
URI:	http://eprints.uthm.edu.my/id/eprint/12806

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