SARS-CoV-2: from origin to treatment and control management strategies

Hezam, Kamal and Almansoub, Hasan and Al-Gheethi, Adel and Saleh, Fuad and Almansob, Yusra and Al-Mekhlafi, Hanadi and Al-Yousofi, Asma and Almezgagi, Maged and Al-Shaebi, Fadhl and Murshed, Dina (2020) SARS-CoV-2: from origin to treatment and control management strategies. In: Covid-19 Pandemic. Penerbit UTHM, pp. 35-63. ISBN 978-967-2389-64-4

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Abstract

The emergence of novel coronavirus (SARS-CoV-2) is marked as the highest pathogenic coronavirus that has crossed from the hosts to the human population in the twenty-first century. The spreading of COVID-19 in different Chinese cities and around the world is travel-related viral spread with the unprecedented nosocomial outbreaks. It has also shown with high case-fatality rates, indeed to urgent prophylactic and therapeutic settings. Scientific advancements of the SARS-CoV-2 pandemic allowed for rapid progress to understand the epidemiology and pathogenesis of SARS-CoV-2. This review highlights the genomic structure of SARS-CoV-2 with the proposed roles of genotype and phenotype of SARS-CoV-2 in pathogenesis and discusses recent results supporting treatment strategies of COVID-19 with a particular focus on how these new insights may facilitate rational development of SARS-CoV-2 for targeted therapies in the future.

Item Type:	Book Section
Uncontrolled Keywords:	Novel Coronavirus; SARS-COV-2; pneumonia; Betacorona virus; interspecies transmission
Subjects:	R Medicine > RA Public aspects of medicine
Divisions:	Faculty of Civil Engineering and Built Environment > Department of Civil Engineering : Water and Environmental Engineering
Depositing User:	Mrs. Siti Noraida Miskan
Date Deposited:	02 Nov 2021 03:47
Last Modified:	02 Nov 2021 03:47
URI:	http://eprints.uthm.edu.my/id/eprint/2254

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