Pathophysiology, histopathology and therapeutic of SARS-CoV-2

Noman, Efaq and Al-Gheethi, Adel and Radin Mohamed, Radin Maya Saphira and Al-Shorgani, Najeeb and Talip, Balkis and Hezam, Kamal and Othman, Norzila (2020) Pathophysiology, histopathology and therapeutic of SARS-CoV-2. In: Covid-19 Pandemic. Penerbit UTHM, pp. 64-76. ISBN 978-967-2389-64-4

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Abstract

The rapid transmission of SARS-CoV-2 through the world has induced the scientist to understand the histopathology of the virus and then to find an effective drug. However, many of the point associated with the virus pathogenicity still unknown and need more studies. In this chapter the pathophysiology, histopathology and therapeutic of SARS-CoV-2 has been reviewed. It was appeared that pathogenicity of SARS-CoV-2 is belonging to the viral with genome structure which acting by blocking the host innate immune response. Both chloroquine and hydroxyl-chloroquine have similar structure and mechanism action and they are among the most effective antiviral for treating the patents with the SARS-CoV-2. Chloroquine works by inhibition the intracellular organism by increasing the pH.

Item Type:	Book Section
Uncontrolled Keywords:	Histopathology; Chloroquine, mechanism; covid-19
Subjects:	R Medicine > RA Public aspects of medicine
Divisions:	Faculty of Civil Engineering and Built Environment > Department of Civil Engineering : Water and Environmental Engineering
Depositing User:	Mrs. Siti Noraida Miskan
Date Deposited:	02 Nov 2021 03:47
Last Modified:	02 Nov 2021 03:47
URI:	http://eprints.uthm.edu.my/id/eprint/2255

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