Numerical analysis on the effect of normotensive and hypertensive physiological conditions onto hemodynamic characteristics in stented carotid artery

Paisal, Muhammad Sufyan Amir and Taib, Ishkrizat and Ismail, Al Emran and Tajul Arifin, Ahmad Mubarak (2019) Numerical analysis on the effect of normotensive and hypertensive physiological conditions onto hemodynamic characteristics in stented carotid artery. International Journal of Mechanical & Mechatronics Engineering IJMME, 19 (1). pp. 94-107. ISSN 2227-2771

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Abstract

An arterial re-blockage or restenosis by abnormal atherosclerosis and thrombosis progression in carotid artery is associated with the geometry of the implanted medical device, called as stent. However, the physiological conditions consisting of normotensive and hypertensive blood flow in the stented carotid artery are rarely studied in term of hemodynamic characteristic especially near the geometry of the stent strut. Thus, the objective of this study is to determine the hemodynamic effect based on its characteristics at different stent strut configurations in carotid artery as well as analyzing the critical parameters at varying blood physiological conditions. Six different geometries of stent that resembles the existing medical device have been studied at three varying physiological conditions of blood. The study was conducted through computational fluid dynamic (CFD) method to analyze the hemodynamic characteristics of the blood flow parameters. In overall physiological condition, the stent geometry of Type VI which are resembling to Acculink (Abbott Vascular), had been shown to have the best hemodynamic characteristic by the parameters of time averaged wall shear stress low (TAWSSlow), oscillatory shear index (OSI) and relative residence time (RRT), which contributed with average luminal surface area percentage about 10.443%, 99.849% and 98.736%, respectively. As the physiological condition of blood flow increased from normotensive to hypertensive, there were two parameters shown to have critical hemodynamic characteristics at different stent geometries which are TAWSSlow and time averaged wall shear stress gradient (TAWSSG) that achieved about 32.388% and 36.629%, respectively. The study had shown that the different stent strut geometries had presented different hemodynamic characteristics due to the effect by the blood flow physiological condition.

Item Type:	Article
Uncontrolled Keywords:	carotid artery; stent geometry; CFD; hemodynamic characteristic; normotensive; hypertensive
Subjects:	R Medicine > RC Internal medicine
Divisions:	Faculty of Mechanical and Manufacturing Engineering > Department of Mechanical Engineering
Depositing User:	Miss Afiqah Faiqah Mohd Hafiz
Date Deposited:	24 Nov 2021 02:16
Last Modified:	24 Nov 2021 02:16
URI:	http://eprints.uthm.edu.my/id/eprint/4064

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