Finite element analysis of osteoporotic vertebrae with first lumbar (L1) vertebral compression fracture

Mazlan, M. H. and Todo, M. and Takano, Hiromitsu and Yonezawa, Ikuho (2014) Finite element analysis of osteoporotic vertebrae with first lumbar (L1) vertebral compression fracture. International Journal of Applied Physics and Mathematics, 4 (4). pp. 267-274. ISSN 2010-362X

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The aim of this work is to assess the biomechanical response or load transfer response between osteoporotic (with first lumbar (L1) vertebral compression fracture) and healthy vertebrae in five vertebral physiological motions namely as compression, flexion, extension, lateral bending and axial rotation. For this purpose, an image-based heterogeneous three-dimensional patient-specific of lumbar and thoracic spinal unit (T12-L2) finite element models for healthy and osteoporotic subjects were created. The finite element analysis have shown that one of the most significant effects of osteoporosis is the tendency to produce higher stress and strain in the cancellous region of the vertebral body. The maximum stress and strain was 4.53 fold (compression) and 5.43 fold (axial rotation) higher for the osteoporotic than the healthy subject, respectively, under the similar loading activity. Uneven stress distribution patterns also have been detected in the osteoporotic vertebrae rather than the healthy vertebrae. All of these characteristics are reflected by a reduced structural strength and bone mass which might lead to an increased risk of fracture. These results strengthen the paradigm of a strong relationship between osteoporosis and its high susceptibility to fracture.

Item Type: Article
Uncontrolled Keywords: Biomechanics; Finite element analysis; Osteoporosis; Vertebrae
Subjects: R Medicine > RC Internal medicine
Divisions: Faculty of Mechanical and Manufacturing Engineering > Department of Mechanical Engineering
Depositing User: Mrs. Siti Noraida Miskan
Date Deposited: 28 Nov 2021 07:19
Last Modified: 28 Nov 2021 07:19

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