Synthesis of bioactive calcium phosphate from cockle shell for biomedical applications

Mohd Pu’ad, Nor Atiqah Syafinaz and Te Chuan, Lee and Salman, Nor Syazwani and Selimin, Mohamad Ali and Abdul Latif, Amirul Faiz and Muhamad, Mimi Suliza and Abdullah, Hasan Zuhudi and Idris, Maizlinda Izwana and Mustapha, Siti Noor Hidayah (2020) Synthesis of bioactive calcium phosphate from cockle shell for biomedical applications. Biointerface Research in Applied Chemistry, 10 (4). pp. 5787-5791. ISSN 2069-5837

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The present work reports the synthesis of bioactive calcium phosphate from cockle shell via the combination of calcination and hydrothermal process. The raw cockle shells were pre-treated with 30 % of hydrogen peroxide for 4 days to eliminate the impurities. Afterward, the dried cockle shells were crushed and calcined at various temperatures ranging from 300 to 1100 °C. Subsequently, the calcined powders underwent hydrothermal process in di-ammonium hydrogen phosphate and distilled water at pH of 10.5 for 30 minutes. Lastly, the hydrothermal treated powders were dried in oven at 50 °C for 3 days. The results showed that the mixture of aragonite, calcite, hydroxyapatite, and calcium hydroxide was successfully synthesized at a calcination temperature of 900 °C and 1100 °C. In addition, the nanorods in the length of 80-300 nm were formed. The findings of this work indicate that the cockle shell could be transformed into valuable bioactive materials for biomedical applications.

Item Type: Article
Uncontrolled Keywords: cockle shell; aragonite; calcite; hydroxyapatite; calcium hydroxide; biomedical.
Subjects: R Medicine > R Medicine (General) > R856-857 Biomedical engineering. Electronics. Instrumentation
Divisions: Faculty of Technology Management and Business > Department of Production and Operation Management
Depositing User: Mr. Shahrul Ahmad Bakri
Date Deposited: 28 Feb 2022 06:46
Last Modified: 28 Feb 2022 06:46

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