Non-invasive estimation of blood oxyhemoglobin and carboxyhemoglobin saturations using cumulant based forward model

Huong, Audrey Kah Ching and Philimon, Sheena P. and Ngu, Xavier T.I. (2015) Non-invasive estimation of blood oxyhemoglobin and carboxyhemoglobin saturations using cumulant based forward model. In: International Conference on Electrical and Electronic Engineering 2015 (IC3E 2015), 10-11 August 2015 , Melaka, Malaysia.

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Abstract

This paper aims to study the feasibility of using optical reflectance spectroscopy and Cumulant based forward model (CM) for non-invasive investigation of differences in mean blood oxyhemoglobin (SmO2) and carboxyhemoglobin saturations (SmCO) amongst the participated smoking and nonsmoking recruits, and the effects of different smoking characteristics of smokers on the predicted SmCO level. The value of SmO2 and SmCO is given by those that produce the best agreement between the employed CM and measurement data optimized using the developed fitting routine. The fitting algorithm required the use of extinction coefficients of hemoglobin components as the background information. This work conducted reflectance point spectroscopy measurement on right index finger of seventeen smoking and eleven nonsmoking Asian volunteers at resting condition. The quantitative analysis of the collected data using the employed CM and fitting strategy revealed SmO2 and SmCO with mean value of 88 ± 2.2% and 4.6 ± 3.6% , respectively, for the nonsmoking population. Meanwhile mean SmO2 of 78 ±10% and mean SmCO of 7.6 ± 5.6% are estimated for the smoking volunteers. These blood saturation values agreed acceptably well with the value reported in literature. This preliminary study found a high correlation between one’s CO poisoning level and their number of years smoked but no relationship is observed between the poisoning level and one’s average daily cigarette consumption.

Item Type:Conference or Workshop Item (Paper)
Uncontrolled Keywords:cumulant based forward model; mean blood oxygen saturation; mean blood carboxyhemoglobin saturation; skin oximetry; spectroscopy
Subjects:R Medicine > R Medicine (General)
Divisions:Faculty of Electrical and Electronic Engineering > Department of Electronic Engineering
ID Code:7155
Deposited By:Normajihan Abd. Rahman
Deposited On:29 Oct 2015 14:15
Last Modified:29 Oct 2015 14:15

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