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A two component red blood cell model for single cell mechanic

Ahmad, Ida Laila and Ahmad, Mohd Ridzuan (2015) A two component red blood cell model for single cell mechanic. ARPN Journal of Engineering and Applied Sciences, 10 (19). pp. 8885-8893. ISSN 18196608

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Abstract

This work presents the deformation of red blood cell (RBC) as it travels in a microchannel using a theoretical model. The developed model predicts the deformation experienced by the RBC when exposed to shear stresses (fluid) as a function of mechanical properties. RBC is known to be a biconcave disk and is modeled as a liquid enclosed with a solid membrane. Therefore it is appropriate to model the RBC as a two component models consists of membrane and cytoplasm. The membrane, assumed to behave as a nearly incompressible material shows hyperelastic response to bending and shearing while the cytoplasm exhibits homogeneous Newtonian fluid properties. The model parameters were determined from the experimental measurements and comparison was made. Agreement in terms of hyperelasticity, deformation rate and stress distribution were found with previous researches.

Item Type: Article
Uncontrolled Keywords: Red blood cell; theoretical model; membrane; cytoplasm; hyperelasticity
Subjects: Q Science > Q Science (General)
Depositing User: Mr. Mohammad Shaifulrip Ithnin
Date Deposited: 13 Aug 2018 03:13
Last Modified: 13 Aug 2018 03:13
URI: http://eprints.uthm.edu.my/id/eprint/10278
Statistic Details: View Download Statistic

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