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Technological advancements in characterizing single cell’s stiffness properties- a review

Ahmad, Ida Laila and Ahmad, Mohd Ridzuan (2014) Technological advancements in characterizing single cell’s stiffness properties- a review. In: 2014 IEEE Conference on Biomedical Engineering and Sciences, 8–10 Dec 2014, Miri, Sarawak.

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Abstract

Biophysical properties of living cells certainly play important roles for intra and intercellular biological events. However, conventional population approaches obscured cells heterogeneity and assume all cells are similar. With the introduction of single cell analysis, this limitation is slowly rectified by defining crucial methods to further revealing cell-to-cell variability. Research in biomechanics leads to better elucidation of cellular and molecular changes due to disease progression i.e diseased cell exhibits different mechanical properties as compared to healthy ones. This paper highlights on various technological advancements available for single cell stiffness characterizations and analytical comparison of the reviewed methods will be thoroughly discussed. In addition, several applications intended for early disease detection were presented.

Item Type: Conference or Workshop Item (Paper)
Subjects: Q Science > QR Microbiology
Divisions: Faculty of Electrical and Electronic Engineering > Department of Electronic Engineering
Depositing User: Mr. Mohammad Shaifulrip Ithnin
Date Deposited: 25 Sep 2018 08:20
Last Modified: 25 Sep 2018 08:20
URI: http://eprints.uthm.edu.my/id/eprint/10382
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