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Development of theoretical oxygen saturation calibration curve based on optical density ratio and optical simulation approach

Jumadi, Nur Anida and Gan, Kok Beng and Mohd Ali, Mohd Alauddin and Zahedi, Edmond and Morsin, Marlia (2017) Development of theoretical oxygen saturation calibration curve based on optical density ratio and optical simulation approach. In: Proceedings of the International Conference on Electrical and Electronic Engineering (IC3E 2017), 14–15 August 2017, Johor, Malaysia.

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Official URL: doi:10.1063/1.5002042

Abstract

The implementation of surface-based Monte Carlo simulation technique for oxygen saturation (SaO2) calibration curve estimation is demonstrated in this paper. Generally, the calibration curve is estimated either from the empirical study using animals as the subject of experiment or is derived from mathematical equations. However, the determination of calibration curve using animal is time consuming and requires expertise to conduct the experiment. Alternatively, an optical simulation technique has been used widely in the biomedical optics field due to its capability to exhibit the real tissue behavior. The mathematical relationship between optical density (OD) and optical density ratios (ODR) associated with SaO2 during systole and diastole is used as the basis of obtaining the theoretical calibration curve. The optical properties correspond to systolic and diastolic behaviors were applied to the tissue model to mimic the optical properties of the tissues. Based on the absorbed ray flux at detectors, the OD and ODR were successfully calculated. The simulation results of optical density ratio occurred at every 20 % interval of SaO2 is presented with maximum error of 2.17 % when comparing it with previous numerical simulation technique (MC model). The findings reveal the potential of the proposed method to be used for extended calibration curve study using other wavelength pair.

Item Type: Conference or Workshop Item (Paper)
Subjects: T Technology > TP Chemical technology > TP250-261 Industrial electrochemistry
Divisions: Faculty of Electrical and Electronic Engineering > Department of Electronic Engineering
Depositing User: Mr. Mohammad Shaifulrip Ithnin
Date Deposited: 30 Sep 2019 03:22
Last Modified: 30 Sep 2019 03:22
URI: http://eprints.uthm.edu.my/id/eprint/11683
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