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Investigation of pulsed electric field on cancer cell cultured on patterned surface

Abd Rahman, Nur Adilah and Abdul Jamil, Muhammad Mahadi (2016) Investigation of pulsed electric field on cancer cell cultured on patterned surface. In: 2016 6th IEEE International Conference on Control System, Computing and Engineering, 25-27 November 2016, Penang, Malaysia.

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Abstract

Electroporation (EP) is a method of controlling cell function by using pulses of electrical fields to create a pore through a cell membrane and causes other substance around it to be absorbed into the cell. Where this method had been led to a variety of medical applications. In this study, we will use voltage of electroporation is 2000V/cm with pulse electric field of 30llS and single pulse to the HeLa Cell (Human Cervical cancer cell) that used as a primary cell in this study. Other than that, we also study the effect of protein surface with parameter of pulsed elctric field mention above. Which are the comparison effect of HeLa cell with protein surface and an empty surface of substrate In certain cases, it is important for the cell to be in the specific location. Which also we studies on microcontact printing (IlCP) method, it is a quite useful technique for patterning extracellular matrix as an adhesion molecule for cells that works for controlling the cell growth. By this two method which is EP and IlCP method, we will combine this with the method in an experiment in order to see the effect of EP technique on cell properties cultured on micropatterned surface.

Item Type: Conference or Workshop Item (Paper)
Uncontrolled Keywords: Electroporation; microcontact printing; cell proliferation; wound healing
Subjects: T Technology > TK Electrical engineering. Electronics Nuclear engineering > TK1001-1841 Production of electric energy or power. Powerplants. Central stations
Divisions: Faculty of Electrical and Electronic Engineering > Department of Electronic Engineering
Depositing User: Mr. Mohammad Shaifulrip Ithnin
Date Deposited: 30 Sep 2019 03:22
Last Modified: 30 Sep 2019 03:22
URI: http://eprints.uthm.edu.my/id/eprint/11684
Statistic Details: View Download Statistic

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