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The application of extended modified Lambert Beer model for measurement of blood carboxyhemoglobin and oxyhemoglobin saturation

Huong, Audrey Kah Ching and Ngu, Xavier (2014) The application of extended modified Lambert Beer model for measurement of blood carboxyhemoglobin and oxyhemoglobin saturation. Journal of Innovative Optical Health Sciences, 7 (3). ISSN 1793-5458

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Abstract

This work presents the use of extended Modified Lambert Beer (MLB) model for accurate and continuous monitoring of percent blood carboxyhemoglobin (COHb) (SCO) and oxyhemoglobin (OxyHb) saturation (SO2) via a ¯tting procedure. This quanti¯cation technique is based on the absorption characteristics of hemoglobin derivatives in the wavelength range of 520–600 nm to give the best estimates of the required parameters. A comparison of the performance of the developed model and MLB law is made using attenuation data from Monte Carlo simulations for a two-layered skin model. The results revealed a lower mean absolute error of 0:4% in the values estimated by the developed model as compared to 10% that is given by the MLB law. This study showed that the discussed approach is able to provide consistent and accurate measurement of blood SO2 and SCO across different skin pigmentations suggesting that it may potentially be used as an alternative means for clinical diagnosis of carbon monoxide (CO) poisoning.

Item Type: Article
Uncontrolled Keywords: blood carboxyhemoglobin saturation; carbon monoxide poisoning; blood oxyhemoglobin saturation; modified Lambert Beer law
Subjects: R Medicine > RA Public aspects of medicine
Divisions: Faculty of Electrical and Electronic Engineering > Department of Electronic Engineering
Depositing User: Normajihan Abd. Rahman
Date Deposited: 26 Aug 2015 07:09
Last Modified: 26 Aug 2015 07:09
URI: http://eprints.uthm.edu.my/id/eprint/6993
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