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Garcinia dulcis fruit extract induced cytotoxicity and apoptosis in HepG2 liver cancer cell line

Abu Bakar, Mohd Fadzelly and Ahmad, Nor Ezani and Suleiman, Monica and Rahmat, Asmah and Isha, Azizul (2015) Garcinia dulcis fruit extract induced cytotoxicity and apoptosis in HepG2 liver cancer cell line. BioMed Research International, 2015. ISSN 2314-6133

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Abstract

Garcinia dulcis or locally known in Malaysia as “mundu” belongs to the family of Clusiaceae.The study was conducted to investigate the anticancer potential of different parts of G. dulcis fruit extracts and their possible mechanism of action in HepG2 liver cancer cell line. MTT assay showed that the peel, flesh, and seed extracts of G. dulcis induced cytotoxicity in HepG2 cell line with IC50 values of 46.33 ± 4.51, 38.33 ± 3.51, and 7.5 ± 2.52

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Applied Science and Technology > Department of Technolgy and Heritage
Depositing User: Normajihan Abd. Rahman
Date Deposited: 01 Feb 2016 07:29
Last Modified: 01 Feb 2016 07:29
URI: http://eprints.uthm.edu.my/id/eprint/7439
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