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Investigation of electroporation technique on cell properties cultured on self-assembled monolayer

Salim, Safyzan and Abd Rahman, Nur Adilah and Abdul Jamil , Muhammad Mahadi and Youseffi, Mansour and Denyer, Morgan C. T. (2016) Investigation of electroporation technique on cell properties cultured on self-assembled monolayer. Journal of Biological Sciences, 16 (7). pp. 278-283. ISSN 17273048

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Electroporation (EP) is a method of controlling cell function by using pulses of electrical fields to create pore through a cell membrane and causes other substance around it to be absorbed into the cell. Where this method had been led to a variety of medical applications. While, micro contact printing (μCP) is a quite useful technique for patterning extracellular matrix as an adhesion molecule for cells that works for controlling the cell growth. This study focuses on a comparison of a cancer cell (HeLa cancer cell) cultured on two different type of substrates which is a protein surface and empty surface. In order to see the effect of cell proliferation of cancer cell with protein solution, which is in this experiment we used fibronectin for the protein solution and the preliminary result show a positive respond to the protein solution that act as self-assembled monolayer.

Item Type: Article
Uncontrolled Keywords: uCP; Hela cancer cell; fibronectin; SAMs; PDMS
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions: Faculty of Electrical and Electronic Engineering > Department of Electronic Engineering
Depositing User: Mr. Mohammad Shaifulrip Ithnin
Date Deposited: 13 Aug 2018 03:25
Last Modified: 13 Aug 2018 03:25
URI: http://eprints.uthm.edu.my/id/eprint/8797
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