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The effect of anatase on rutile TiO2 nanoflowers towards its photo-catalytic activity on cancer cells

Khalid, Noor Sakinah (2016) The effect of anatase on rutile TiO2 nanoflowers towards its photo-catalytic activity on cancer cells. Masters thesis, Universiti Tun Hussein Onn Malaysia.

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Titanium dioxide (TiO2) rutile nanoflowers were fabricated using acidic hydrothermal method. TiO2 nanoflowers were successfully grown on fluorine doped tin oxide (FTO) substrates. The hydrothermal reaction time and amount of titanium butoxide (TBOT) precursors were optimized to be 10 hours and 2 ml, respectively. Fabrication of TiO2 using spray pyrolysis technique produced TiO2 nanoparticles. The surface morphology of the TiO2 nanoflowers and nanoparticles were studied using Field Emission Scanning Electron Microscope (FESEM) to detect the changes in surface morphology as a result of varied parameters. The crystalline phases of TiO2 samples were investigated using X-ray Diffractions (XRD). From the XRD analysis, TiO2 nanoflowers produced using the hydrothermal method were of rutile phase while TiO2 nanoparticles produced using the spray pyrolysis technique were of anatase phase. Thus, when the two fabrication processes were mixed, anatase-rutile phased TiO2 particles were produced. Photo-degradation of TiO2 nanoflowers were analyzed using methyl orange dye. UV-Vis-NIR spectrophotometer was used to observe the absorbance of methyl orange before and after UV light exposure to the TiO2 samples. The degradation rates of methyl orange by rutile, anatase-rutile and anatase were 4.35%, 88.8% and 98%, respectively. Thereon, cervical cancer cells were exposed to the TiO2 samples to check the biocompatibility of the fabricated TiO2. The cervical cancer cells showed biocompatibility towards the fabricated TiO2. Lastly, photo-catalytic activity of the fabricated TiO2 was studied on cancer cells. The fabricated TiO2 showed little effect to the cancer cells as no change in cell size were observed after UV exposure due to the low electron excitation on TiO2 surface. Thus, the photo-catalysis reaction did not occur.

Item Type: Thesis (Masters)
Subjects: Q Science > QD Chemistry
Depositing User: Mr. Mohammad Shaifulrip Ithnin
Date Deposited: 06 Feb 2017 06:58
Last Modified: 06 Feb 2017 06:58
URI: http://eprints.uthm.edu.my/id/eprint/8850
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