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An alternative means of spectroscopic imaging for superficial wound healing process monitoring

Philimon, Sheena Punai (2016) An alternative means of spectroscopic imaging for superficial wound healing process monitoring. Masters thesis, Universiti Tun Hussein Onn Malaysia.


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To date, oximetry is considered as an ideal approach to monitor one's microcirculation. Quantitative information of wound tissue oxygenation is beneficial for proper wound care in response to different treatment. The conventional method of oximetry using a fingertip pulse oximeter is limited to certain body parts and required contact, hence, is deemed unsuitable for wound assessment. This research describes a non-invasive and non-contact multispectral spectroscopy approach for optical monitoring of changes in oxyhemoglobin saturation level during wound healing process. Non-contact reflectance data captured from the wounded skin site using a monochromatic imaging system in the wavelength range of 520−600 nm are mathematically analyzed and fitted using Extended Modified Lambert Beer model to give the best estimation of percent transcutaneous oxygen saturation, StO2. Experimental works conducted on ten Asian subjects with different wound sites revealed progressive changes in StO2 level throughout the healing process. The results revealed a significant increase in StO2 that reaches its peak in between fourth and sixth day of wound healing. Quantitative analysis of wound oxygenation level using line profiler based on StO2 mapping shows high StO2 values of greater than 90% in wounded skin sites while StO2 in the range of 30−50% is observed along the adjacent unwounded skin region. The results from this study show feasibility of using this technique to provide visual progression of wound via tissue oxygenation status, suggesting the prospective implementation of this system in hospitals as an alternative means to assess wound healing.

Item Type: Thesis (Masters)
Subjects: T Technology > TK Electrical engineering. Electronics Nuclear engineering > TK7800-8360 Electronics
Depositing User: Mr. Mohammad Shaifulrip Ithnin
Date Deposited: 12 Feb 2017 07:18
Last Modified: 12 Feb 2017 07:18
URI: http://eprints.uthm.edu.my/id/eprint/8873
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