Parametric optimization of the femoropopliteal artery stent design based on numerical analysis

Kareem, Ali Kamil (2021) Parametric optimization of the femoropopliteal artery stent design based on numerical analysis. Doctoral thesis, Universiti Tun Hussein Onn Malaysia.

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Abstract

High-failure rates of Peripheral Arterial Disease (PAD) stenting were reported due to the inability of certain stent strut configuration to accommodate severe biomechanical environment of the Femoro-Popliteal Artery (FPA) such as bends, twists, and axially compresses during limb flexion. The unique of mechanical deformation environment in FPA has been considered one of main factors affecting the durability of the FPA stent and reducing the stent life. Consequently, various optimization techniques have been developed to improve the mechanical performance of the FPA stent. The present work shown that, the first-two of twelve FPA resemble stent models stent models have been selected with a net score of 3.65 Model I and, with a net score of 3.55 Model II via applying Pictorial Selection Method. Finite Element Method (FEM) of optimization study based-parameterization has been conducted for stent strut dimensions, stents were compared in terms of force-stress behavior. Multi Criteria Decision Making (MCDM) method has been utilized to identify the best combination of strut dimensions. The strut thickness parameterization results were in relation T α 1/σ (T is strut thickness) for both models with all mechanical loading modes. Moreover, the strut width parameterization results were in relation W α 1/σ (W is strut width) for both models with all mechanical loading modes. Whereas, the strut length parameterization results were in relation L α σ in case of Model I and, L α 1/σ (L is strut length) in case of Model II, under axial loads, while under three-point bending and torsion loading modes L α σ for both models, under radial compression the relations were L α 1/σ in case of Model I and, L α σ in case of Model II. The best combination of strut dimension in the thickness case was t4 = 230 µm for both models, in strut width were w3=0.180, and w4= 0.250 mm for Model I and Model II, respectively, and in strut length were l2= 1.40, and l2= 1.75 mm for Model I and Model II, respectively. In conclusions, the mathematical selection approach and the consistent mathematical approach of MCDM has been proposed, also the mechanical performance has been improved for parameterized stent models.

Item Type:	Thesis (Doctoral)
Subjects:	R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine T Technology > T Technology (General)
Divisions:	Faculty of Mechanical and Manufacturing Engineering > Department of Mechanical Engineering
Depositing User:	Mrs. Sabarina Che Mat
Date Deposited:	03 Feb 2022 02:33
Last Modified:	03 Feb 2022 02:33
URI:	http://eprints.uthm.edu.my/id/eprint/4130

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